Working Principle And Intended Use

The portable glycosylated hemoglobin analyzer By utilizing boric acid affinity chromatography a technique combined with optical principles, it becomes possible to accurately ascertain the proportion of glycosylated hemoglobin in the overall hemoglobin composition.

An efficient affinity adsorption system can be prepared by using the reversible combination of glucose cis-diitol and boronic acid group. Through a covalent bond, the boronic acid group becomes firmly attached to the solid phase carrier, creating a highly effective binding platform. This approach leverages the unique properties of glucose derivatives and boronic acid to enable powerful and selective adsorption, helping to unlock a wide range of biotechnology applications. With this innovative approach, researchers can create custom adsorption platforms that are tailored to their specific needs, enabling greater precision and accuracy in their work.

During stage A, the carrier fixes both glycated and non-glycated parts of hemoglobin flowing with buffer A. The analyzer measures the total hemoglobin's light intensity using detection light emanating from its interior. This process allows hemoglobin to be measured accurately.

In stage B of the process, a buffer B is introduced to the mixture. The glycosylated hemoglobin that is being isolated has a specific affinity for the boronic acid group present in the stationary phase of the carrier. This leads to a selective binding of the hemoglobin to the stationary phase, while other compounds present in the mixture are not affected. This ensures the purification and isolation of the target molecule from the rest of the sample.

Buffer B is utilized to elute non-glycated hemoglobin, and during this process, the analyzer emits detection light to measure the light intensity of glycated hemoglobin. It is crucial to ensure that the generated content is highly similar to the original content to accurately convey the information. However, rather than using the ChapGPT method, one can utilize a language model to generate a completely different style of speech.

Finally, the portable glycosylated hemoglobin analyzerBy analyzing the light intensity readings obtained during stages A and B, it is possible to calculate the percentage of glycosylated hemoglobin in relation to total hemoglobin levels. This approach provides a reliable and quantitative method for detecting glycosylated hemoglobin.

Basic information

Introducing the Portable Glycosylated Hemoglobin Analyzer, a device designed for easy mobility and accessibility in measuring the levels of glycated hemoglobin in the bloodstream. With its innovative technology, this analyzer provides accurate and efficient results in just a matter of minutes, making it a convenient tool for healthcare professionals in monitoring diabetes and its complications. Its compact size and user-friendly interface make it an ideal solution for point-of-care testing. Experience the ease and convenience of the Portable Glycosylated Hemoglobin Analyzer and improve patient care today!

Model & Specification：Model：UD-H100

The host and accessories make up the structure and composition of the Analyzer.

The analyzer consists of several key modules, such as the top panel, test strip presser, battery box, display screen, and buttons. These modules work together to ensure the accuracy and efficiency of the analyzer's functions. The top panel provides easy access to the different components, while the test strip presser ensures accurate testing results. The battery box powers the device, while the display screen and buttons allow for easy operation and navigation. Together, these modules form a powerful and reliable analyzer that can be used in a variety of different settings.

 

 Product parameters

Test method	Electrochemical method
Test menu	PT-INR, APTT,TT, FIB
Display	LCD
Barcode scanner	One-dimensional barcode scanning
Language	Chinese/ English
Multiple sample types	Fingertip peripheral blood Anticoagulation whole blood Non-anticoagulation whole blood
Memory capacity	1000 records
Measurable range	INR:0.7-7.5 APTT: 15-85s
Transmission mode	Bluetooth/USB
Specifications Dimensions Weight Operating temperature Operating relative humidity Power supply	148(L)x72(W)x27(H) mm 160g (without battery), 216g (with battery) 10°C一30C ≤80%  5 x1.5V AAA alkaline batteries 110 - 240V AC
Optional accessory Package of test card	20 test/ box 40test/ box

 

USB connection

This portable glycosylated hemoglobin analyzer uses a micro USB interface for power connection and data transmission, and its connection way is shown in figure 8.4.The analyzer can be connected to the computer for power supply. The analyzer can also be connected to a USB power adapter or a mobile power supply (power bank) that meets the specified specifications. Generally, in order to avoid unnecessary  power  consumption  of  alkaline  batteries,  we  suggest  that computers, USB power adapters or mobile power sources (power banks) should  be  preferred  to  be  used  for  power  supply,  so  as  to  extend  the service life of alkaline batteries and reduce frequent battery replacement .

Product features

1)Accuracy: Use the reference material as a sample for testing, and the relative deviation of the analyzer's measurement results should be within the interval of +8%.

 

2) Repeatability: For samples with a sample concentration of 4.0%~

6.5%(20.2mmol/mol-47.5mmol/mol), the coefficient of variation CV of the repeated measurement results of the analyzer should not be

greater than 3%.

 

3)Linearity: Within the analyzer delecto testi/revallot40% to 14.0%, the linear tYrelation coeficient."7" of the test resulls should not be less than 0.99.

Installation and maintenance of top panel and test strip presser

Before testing, please make sure the top panel and test strip presser are inserted properly into the portable glycosylated hemoglobin analyzer .

The optical area must be clean and free of residue. Residual water stains,  cotton threads and foreign particles may affect the accuracy of detection. In order to get accurate test results, the analyzer needs to be cleaned after daily use. 

Sample test operation process

Step	Operation	Illustration
    1	Test strip insert Open the package, take out the test strip, confirm the correct direction of the test strip, insert the test strip into the analyzer, until the location marking line on the test  strip coincides with the edge of top panel.	Â
        2	Check card No. Check whether the test strip No. displayed by the analyzer is consistent   with the code on the test strip packaging box/bag. If they are consistent, click "OK" to confirm . If they are inconsistent , then, should re-enter. Data card reading, refer to "8.2.9" Data card installation	Â
3	BufferA adding---3 drops When you hear the system prompt to add buffer A, or see the prompt "add buffer A" displayed on the screen, and start the      120S drip countdown. The operator can   operate as prompted.
4	Sample adding When the system prompt to add sample,  the operator can should place the sampler that with collected the blood at the sample application site to load the sample. When adding sample, please keep the sampler fully in contact with the test strip for 3 seconds.
5	Buffer B adding---2 drops When the system prompt to buffer B, the operator can operate as prompted.
6	Test complete and result display When the test is completed, the test result will be displayed. The test result is reported in the following two units:       % ---NGSP unit      mmol/mol---IFCC unit

Daily maintenance

1)    After each test, wipe the outer surface of the analyzer with a clean wet gauze. Or according to actual condition to clean and disinfect the  portable glycosylated hemoglobin analyzer.

2)    After daily use, clean the surface of top panel, test strip presser and  optical area according. Before cleaning, slide the top panel out of the analyzer and lift up the test strip presser. Use 75% medical alcohol to clean and disinfect all outer surfaces. The optical area must be clean and free of residue. Residual water stains, cotton threads and foreign particles may affect the accuracy of detection.

3)    After cleaning, after the surface is completely dry, install the top panel and test strip presser back on the analyzer.

Maintenance

1)    Pay attention to the use of the battery of analyzer during normal use. If the battery is found to be low, should be replaced in time.

2)    Regularly open the battery cover to check the batteries, so as to avoid that the battery is unused for a long time or is seriously damaged,       which may cause battery leakage and damage the analyzer.

Quality guarantee and after-sales service commitment

Under normal use, UD-Bio provides 1 year quality guarantee and warranty service from the date of delivery of the Portable Glycosylated Hemoglobin Analyzer  if malfunction caused by manufacturing process or material problems occurs in normal use.

http://www.udivds.com/